Patrice Koehl, Ph.D.

Patrice Koehl

Position Title
Professor

  • Computer Science
He/Him/His
Room 4319, Genome Center, GBSF
451 East Health Sciences Drive, University of California, Davis CA 95616
Bio

Research Interests

  • New algorithms for clustering post-genomic data
  • Powerful geometric methods for processing image data and for comparisons of 3D-images in a high-throughput manner
  • Efficient and robust solvers of partial differential equations to understand the solvation and thermodynamics of drug targets

Selected Works

  • M. Carlsen, P. Koehl, and P. Røgen. On the importance of the distance measures used to train and test knowledge-based potentials for proteins PLoS One, (2014: in press). [ bib ]
  • J. Li and P. Koehl 3D representations of amino acids - applications to protein sequence comparison and classification Comp. Struct. Biotech. J., (2014: in press). [ bib ]
  • C.-P. Chen, H. Fushing, R. Atwill, and P. Koehl biDCG: A new method for discovering global features of DNA microarray data via an iterative re-clustering procedure PLoS One, 9:e102445 2014. [ bib ]
  • H. Fushing, C. Chen, S.H. Liu, and P. Koehl Bootstrapping on undirected binary networks via statistical mechanics J. Stat. Phys. 156:853-862, 2014. [ bib ]
  • V. Weinreb, L. Li, S.N. Chandrasekaran, P. Koehl, M. Delarue, and C.W. Carter. Domain motion sensed by the d1 switch, a remote dynamic packing motif. J. Biol. Chem., 289:4367-4376, 2014. [ bib ]
  • P. Koehl and J. Hass. Automatic alignment of genus-zero surfaces. IEEE Trans. Pattern Anal. Mach. Intell., 36:466-478, 2014. [ bib ]
Education and Degree(s)
  • PhD in Biophysics (Molecular Biology and NMR spectroscopy), Louis Pasteur University, Strasbourg, France
Publications
  • Fast computation of exact solutions of generic and degenerate assignment problems
    Journal Article | Koehl, P., Orland, H. Physical Review E, 103, 042101. 10.1103/physreve.103.042101
  • Parameterizing elastic network models to capture the dynamics of proteins
    Journal Article | Koehl, P., Orland, H., Delarue, M. Journal of Computational Chemistry, 42, 1643-1661. 10.1002/jcc.26701
  • Physics approach to the variable-mass optimal-transport problem
    Journal Article | Koehl, P., Delarue, M., Orland, H. Physical Review E, 103, 012113. 10.1103/physreve.103.012113
  • Simultaneous Identification of Multiple Binding Sites in Proteins: A Statistical Mechanics Approach
    Journal Article | Koehl, P., Delarue, M., Orland, H. The Journal of Physical Chemistry B, 125, 5052-5067. 10.1021/acs.jpcb.1c02658
  • Coarse-grained dynamics of supramolecules: Conformational changes in outer shells of Dengue viruses
    Journal Article | Koehl, P., Delarue, M. Progress in Biophysics and Molecular Biology, 143, 20-37. 10.1016/j.pbiomolbio.2018.09.004
  • See publications and more on Aggie Experts: https://experts.ucdavis.edu/expert/EAEHpM8x